RxCheckUp

RxCheckUp vs Surescripts

Surescripts is a electronic prescribing and epa standards network. Surescripts is the rails that PA messages run on. RxCheckUp produces the actual clinical content — a signable Letter of Medical Necessity — that justifies the request.

Feature-by-Feature Comparison

FeatureRxCheckUpSurescripts
AI-generated Letter of Medical Necessity
ePA message transport (NCPDP SCRIPT)
eRx network
Clinical evidence citations
Payer-specific criteria matching174 payers built inQuestion sets only
Appeal letter drafting
ICD-10 & drug catalog lookup
Time to draft clinical justification2 minutesN/A — transport only
Reachable directly by clinicOnly via integrated EHR
What you getSignable LMN with evidenceRouted PA question set

Key Differentiators

1Network vs content

Surescripts is the network — it carries ePA question sets between your EHR and the PBM. RxCheckUp produces the Letter of Medical Necessity that turns those answers into a defensible clinical argument backed by evidence.

2Works without EHR ePA integration

Many small practices and supplement clinics don’t have ePA wired into their EHR. RxCheckUp generates a signable LMN you can fax, email, or upload to any payer portal — no Surescripts integration required.

3Stronger on appeals

When a PA gets denied, the ePA question set already failed. RxCheckUp drafts the appeal letter that cites the specific denial reason and counters it with evidence.

Start Free Trial →