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Cigna (Express Scripts) Letter of Medical Necessity Guide

How to write an LMN and overturn a prior authorization denial with Cigna (Express Scripts). Includes denial reasons, turnaround times, appeals address, and clinician tips.

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Quick Facts

  • Avg Turnaround: 30 days standard, 72h expedited
  • Appeals Address: Cigna Appeals Unit, PO Box 188011, Chattanooga, TN 37422
  • Provider Portal: https://cignaforhcp.cigna.com/

Why Cigna Denies Prior Authorizations

  1. 1. Step edit not satisfied
  2. 2. Off-label use
  3. 3. Missing genetic testing
  4. 4. Dose exceeds FDA label

Clinician Tips for Cigna

  • ✓ Reference Cigna Coverage Policy (CP) number
  • ✓ Express Scripts handles Rx — submit via CoverMyMeds
  • ✓ Expedited appeals require attestation of urgency

Cigna Coverage Policies are public — link to the exact CP in your LMN.

Cigna Prior Authorization FAQ

Why does Cigna deny prior authorizations?

The most common Cigna denial reasons are: Step edit not satisfied; Off-label use; Missing genetic testing; Dose exceeds FDA label.

How long does Cigna take to review a prior authorization?

Cigna typically responds in 30 days standard, 72h expedited.

What should a Letter of Medical Necessity for Cigna include?

An LMN for Cigna (Express Scripts) should reference the specific medical policy or coverage bulletin, document failed first-line therapies with dates, include current labs and ICD-10 codes, and cite supporting clinical guidelines. Cigna Coverage Policies are public — link to the exact CP in your LMN.